Amitriptyline 25 mg/mL Compounded Transdermal Gel - 1 syringe

Amitriptyline 25 mg/mL Compounded Transdermal Gel provides a veterinarian-prescribed option when an alternative to oral dosing is needed for cats and dogs. Amitriptyline is a tricyclic antidepressant commonly prescribed by veterinarians to help manage anxiety-related behaviors, urine spraying/marking, and stress-associated urinary discomfort in cats (feline idiopathic cystitis). It may also be used as part of a treatment plan for chronic pruritus or neuropathic pain in select patients. This transdermal format is compounded to order at a fixed 25 mg/mL concentration for topical administration as directed by your veterinarian.

$8.28

Amitriptyline 25 mg/mL Compounded Transdermal Gel

By: PMD Labs

Amitriptyline 25 mg/mL Compounded Transdermal Gel

By: PMD Labs
💊 Prescription
This product requires a valid prescription. After you place your order, we'll follow up by email to collect your veterinarian or prescription details. Note: If we don't receive a response within 1 week, we'll cancel the order and issue a full refund — just to keep things safe and compliant.
Subtotal: $8.28
💊 Prescription
This product requires a valid prescription. After you place your order, we'll follow up by email to collect your veterinarian or prescription details. Note: If we don't receive a response within 1 week, we'll cancel the order and issue a full refund — just to keep things safe and compliant.
✓ Free shipping on orders over $100
🚚 Usually delivered in 1-5 days

Amitriptyline 25 mg/mL Compounded Transdermal Gel provides a veterinarian-prescribed option when an alternative to oral dosing is needed for cats and dogs. Amitriptyline is a tricyclic antidepressant commonly prescribed by veterinarians to help manage anxiety-related behaviors, urine spraying/marking, and stress-associated urinary discomfort in cats (feline idiopathic cystitis). It may also be used as part of a treatment plan for chronic pruritus or neuropathic pain in select patients. This transdermal format is compounded to order at a fixed 25 mg/mL concentration for topical administration as directed by your veterinarian.

About This Item

  • A compounded veterinary transdermal gel containing amitriptyline 25 mg/mL, commonly prescribed to help manage anxiety-related behaviors, urine spraying/marking, and stress-associated urinary discomfort in cats, and sometimes used for pruritus or neuropathic pain in dogs and cats as directed by a veterinarian.
  • Amitriptyline

What is amitriptyline used for in pets?

Veterinarians commonly prescribe amitriptyline to help manage anxiety-related behaviors, urine spraying or marking, and stress-associated urinary discomfort in cats (feline idiopathic cystitis). It may also be used for chronic pruritus or neuropathic pain in select dogs and cats.

How do I apply the transdermal gel to my pet?

Apply exactly as your veterinarian directs, typically to a clean, hairless area such as the inner ear pinna in cats. Wear gloves, spread the gel as instructed, and allow it to dry while preventing your pet from grooming the site.

How long before I see results with amitriptyline?

Response time varies by pet and condition. Some pets may show changes within several days, while full benefit may take longer; your veterinarian will advise on expectations and follow-up.

What side effects should I watch for?

Possible side effects can include drowsiness, dry mouth, constipation, urinary retention, or gastrointestinal upset. If you notice agitation, rapid heart rate, marked weakness, or any concerning changes, contact your veterinarian promptly.

Can this be used in both cats and dogs?

Yes. Amitriptyline can be used in both species when prescribed by a veterinarian, and the transdermal route is often chosen for cats that are difficult to medicate orally.

Can amitriptyline be given with other medications?

Always tell your veterinarian about all medications and supplements your pet is taking. Amitriptyline may interact with certain other therapies, so your veterinarian will determine a safe plan and monitor as needed.

What should I do if I miss a dose?

Give the missed dose when you remember unless it is close to the next scheduled dose. Do not double up; resume the regular schedule and consult your veterinarian if you are unsure.

Pet Health Benefits

Every product we carry at PetMeds Direct is selected with care to support your pet's health from nose to tail.

✓

Pain Relief

Vet-approved medications to reduce inflammation and ease joint or post-surgery pain

✓

Heart Health

Supplements and meds that help manage blood pressure and support cardiovascular function

✓

Disease Prevention

Vaccines and immune-boosting supplements help reduce the risk of serious illness

✓

Skin & Coat Care

Dermatology products and omega-rich formulas promote healthy skin and a shiny coat

Happy Pet Parents

Not sure how to get started with PetMeds Direct? We make caring for your pet easier than ever — whether it's managing prescriptions, stocking up on supplements, or getting expert advice. Explore below for helpful ways pet parents use PetMeds Direct to stay on top of their pets' health. At PetMeds Direct, we're proud to serve pet lovers all across Canada.

🐾 Marcus L. - Toronto, ON

"From ordering to delivery, everything was seamless. I even got a helpful reminder email about my dog's monthly flea prevention. PetMeds truly cares about our pets!"

🐶 Jenna R. – Vancouver, BC

"I'm so glad I found PetMeds Direct. They handled everything with my vet directly, and my dog's prescription arrived at my door in just two days."

🐱 Amy Allen - Calgary, AB

"As a cat mom managing ongoing medication, PetMeds has been a total game-changer. They make refills automatic, and I always get a heads-up before anything ships. So reliable!"

About PetMeds Direct

PetMeds Direct was founded with one simple mission: to make pet healthcare easier, faster, and more compassionate for Canadian pet parents. What started as a small idea — helping busy families manage their pets’ prescriptions — has grown into a trusted nationwide pharmacy serving dogs, cats, and everything in between. We believe pets are family, and every tail wag and purr deserves top-tier care. That’s why we work closely with vets, offer fast shipping, and make prescriptions and wellness products more accessible than ever. At PetMeds Direct, we’re not just delivering meds — we’re delivering peace of mind.

Healthy Pets, Happy Homes

Caring for your pet’s health has never been easier. With just a few clicks, PetMeds Direct delivers trusted medications and wellness products right to your door — fast, affordable, and vet-approved. Say goodbye to last-minute pharmacy runs and hello to peace of mind.

Trusted & Certified

PetMeds Direct is a licensed and certified pharmacy, committed to providing safe, authentic medications for your pets.

Accreditation No. 311012