Multi-Duo Plus
Multi-Duo Plus Multi-Duo Plus Multi-Duo Plus Multi-Duo Plus

Multi-Duo Plus is a prescription topical antiparasitic bundle for dogs from Elanco. Each duo pack combines Advantage multi 100 (6 tubes x 4.0 mL) with two boxes of K9 Advantix II X-Large Dog (4 tubes x 4.0 mL each) for convenient at-home use. Available in color-coded weight ranges, it’s designed for topical application as directed. Ideal for pet parents searching for dog health and flea and tick prevention solutions, this pack streamlines your antiparasitic care routine under veterinary guidance. Always follow the individual product labels and your veterinarian’s recommendations.

$163.57

Multi-Duo Plus

By: Elanco

Multi-Duo Plus

💊 Prescription
This product requires a valid prescription. After you place your order, we'll follow up by email to collect your veterinarian or prescription details. Note: If we don't receive a response within 1 week, we'll cancel the order and issue a full refund — just to keep things safe and compliant.
$163.57
Subtotal: $163.57
💊 Prescription
This product requires a valid prescription. After you place your order, we'll follow up by email to collect your veterinarian or prescription details. Note: If we don't receive a response within 1 week, we'll cancel the order and issue a full refund — just to keep things safe and compliant.
✓ Free shipping on orders over $100
🚚 Usually delivered in 1-5 days

Multi-Duo Plus is a prescription topical antiparasitic bundle for dogs from Elanco. Each duo pack combines Advantage multi 100 (6 tubes x 4.0 mL) with two boxes of K9 Advantix II X-Large Dog (4 tubes x 4.0 mL each) for convenient at-home use. Available in color-coded weight ranges, it’s designed for topical application as directed. Ideal for pet parents searching for dog health and flea and tick prevention solutions, this pack streamlines your antiparasitic care routine under veterinary guidance. Always follow the individual product labels and your veterinarian’s recommendations.

About This Item

  • For antiparasitic use in dogs. This duo pack includes Advantage multi 100 and K9 Advantix II X-Large Dog; use only as labeled on each included product. Prescription required in Canada, including Quebec.
1 duo pack
  • Imidacloprid; Moxidectin; Permethrin; Pyriproxyfen
  • Topical

What is included in the Multi-Duo Plus pack?

Each duo pack includes 1 box of Advantage multi 100 (6 tubes x 4.0 mL) and 2 boxes of K9 Advantix II X-Large Dog (4 tubes x 4.0 mL each).

Is Multi-Duo Plus for dogs only?

Yes. Approved Species: Dog. Choose the weight-range that matches your dog before use.

Which size should I choose for my dog?

Select the color-coded option that matches your dog’s weight: GREEN/VERT < 4.5 kg; AQUA 4.6–9 kg; RED/ROUGE 11–25 kg; BLUE/BLEU > 25 kg.

Is a prescription required?

Yes. This product requires a prescription in Canada, including Quebec.

How is it administered?

It is a topical solution. Apply as directed on each product label and follow your veterinarian’s instructions.

Which active ingredients are in this bundle?

The active ingredients are imidacloprid, moxidectin, permethrin, and pyriproxyfen.

Does this cover specific parasites like fleas or ticks?

Refer to the individual labels for Advantage multi 100 and K9 Advantix II for the exact parasite indications and directions for use.

Pet Health Benefits

Every product we carry at PetMeds Direct is selected with care to support your pet's health from nose to tail.

Pain Relief

Vet-approved medications to reduce inflammation and ease joint or post-surgery pain

Heart Health

Supplements and meds that help manage blood pressure and support cardiovascular function

Disease Prevention

Vaccines and immune-boosting supplements help reduce the risk of serious illness

Skin & Coat Care

Dermatology products and omega-rich formulas promote healthy skin and a shiny coat

Happy Pet Parents

Not sure how to get started with PetMeds Direct? We make caring for your pet easier than ever — whether it's managing prescriptions, stocking up on supplements, or getting expert advice. Explore below for helpful ways pet parents use PetMeds Direct to stay on top of their pets' health. At PetMeds Direct, we're proud to serve pet lovers all across Canada.

About PetMeds Direct

PetMeds Direct was founded with one simple mission: to make pet healthcare easier, faster, and more compassionate for Canadian pet parents. What started as a small idea — helping busy families manage their pets’ prescriptions — has grown into a trusted nationwide pharmacy serving dogs, cats, and everything in between. We believe pets are family, and every tail wag and purr deserves top-tier care. That’s why we work closely with vets, offer fast shipping, and make prescriptions and wellness products more accessible than ever. At PetMeds Direct, we’re not just delivering meds — we’re delivering peace of mind.

Healthy Pets, Happy Homes

Caring for your pet’s health has never been easier. With just a few clicks, PetMeds Direct delivers trusted medications and wellness products right to your door — fast, affordable, and vet-approved. Say goodbye to last-minute pharmacy runs and hello to peace of mind.

Trusted & Certified

PetMeds Direct is a licensed and certified pharmacy, committed to providing safe, authentic medications for your pets.

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